Intriguingly, recent research showed that SARS-CoV-2 leveraged species-specific interferon-driven upregulation of angiotensin-converting enzyme 2 (ACE2) to promote infection (the SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues). The gene discussed is ACE2; the disease is infection.