Consistent with a previous study on uterine cervical cancer (20), the correlation between MACC1 and the EMT-related proteins, vimentin and E-cadherin, observed in this study indicate the association between MACC1 and EMT in NPC, thus adding NPC to the list of cancers previously reported to involve EMT (31, 33). This evidence concerns the gene VIM and nasopharyngeal carcinoma.