MACC1, vimentin, and E-cadherin protein levels in NPC tissues were significantly correlated with T stage (p=0.011), N stage (which is synonymous with lymph node metastasis; p=0.013, 0.011, 0.001, respectively), and cancer stages I to IV (p=0.023, 0.037, 0.022, respectively). This evidence concerns the gene CDH1 and metastatic malignant neoplasm in the lymph nodes.