Further examination showed that the expression of selected targetable enzymes in the glycolytic pathway, pyruvate dehydrogenase kinase (PDK) 1–4, and the FAO pathways, acetyl CoA dehydrogenase (ACAD), thiolase [acetyl-coenzyme A acetyltransferase (ACAT)], cronotase (ECH), and HADH, were similarly expressed across the GBM subtypes, except ECH was significantly higher in proneural/neural compared to classical tumors (p = 0.0022; Figure 1B). The gene discussed is HADH; the disease is glioblastoma.