Because certain changes occur in the levels of estrogen, progesterone LH and FSH in pregnancy and abortion, and A. fascicolifolius may contribute to induced abortion through influencing the levels of these hormones, this study was conducted to aim determining abortifacient A. fascicolifolius manna hydroalcoholic extract effect on estrogen, progesterone, LH and FSH levels in BALB/c mice [18, 19]. Here, PLOD1 is linked to abortion.