THADA and endometriosis: PheWAS analysis ([85], from https://genetics.opentargets.org/) of risk SNPs demonstrated comparable patterns: eight of 27 genome-wide significant endometriosis risk SNPs, and six genome-wide significant PCOS risk SNPs, were pleiotropically associated with age of menarche or menopause (or both, for FSHB and THADA SNPs), and five endometriosis risk SNPs, and two PCOS risk SNPs, were pleiotropically associated with WHR or BMI.