Most notably, women with endometriosis exhibit, relative to controls: (1) shorter AGDs, indicative of lower prenatal testosterone [40, 41], (2) lower LH relative to FSH, (3) higher SHBG, (4) higher serum oxytocin, (5) lower ovarian and serum testosterone, (6) lower AMH, (7) lower WHR and BMI, (8) lower β-endorphin and (9) a suite of other differences, all of which are opposite to the differences found between PCOS versus controls [3]. The gene discussed is SHBG; the disease is endometriosis.