Echocardiography analysis at 4 weeks after MI confirmed that knockout of Ripk3 significantly improved the left ventricular ejection fraction (LVEF) and left ventricular fractional shortening (LVFS) and also reduced the internal diameter of the left ventricle at the end of systole and diastole (Figures 2(a)–2(d)). Here, RIPK3 is linked to myocardial infarction.