Most importantly, 91.7% (55/60) of pancreatic cancer specimens and 56.3% (31/55) of adjacent samples had high expression of ERCC3 (Figure 1B), and the staining score of ERCC3 in pancreatic cancer and associated-adjacent tissues was significantly different (p<0.05, χ2 test, Figure 1C). This evidence concerns the gene ERCC3 and familial pancreatic carcinoma.