VEGFA and hepatocellular carcinoma: Although the study has not further determined the specific signaling pathway downstream of miR-155, clinical statistics show that the high expression of exosomal miR-155 in the preoperative plasma of patients with HCC is significantly related to the early recurrence and metastasis of patients, and the results of immunohistochemistry further confirmed that the high expression of exosomal miR-155 was significantly correlated with the expression of VEGF, HIF-1α, and MVD 66.