ELR-containing CXC chemokines can promote angiogenesis and thus promote tumor growth, whereas CXCL9, which is mainly induced by IFN - γ and synthesized in lymphocytes, monocytes, and fibroblasts, as a non-ELR-containing CXC chemokines, can inhibit angiogenesis and thus play a cancer suppressive role. Here, CXCL9 is linked to neoplasm.