CENPF and hepatocellular carcinoma: Meanwhile, subgroup analyses indicated that CENPF upregulation in tumors was a risk factor for 1-year, 3-year and 5-year OS in patients with HCC (HR = 2.29, log rank P = 0.0028; HR = 1.99, log rank P = 0.00058 and HR = 1.68, log rank P = 0.0044, respectively, Figures 5C-E).