MSTN and cancer: Regulatory roles of myostatin have now been discovered in aging, cancer cachexia, insulin sensitivity, diabetes, and in cardiac tissue where myostatin influences inflammation (McPherron and Lee, 2002; Yarasheski et al., 2002; Rodgers and Garikipati, 2008; Guo et al., 2009; Zhang et al., 2011; Biesemann et al., 2014, 2015; Jackson et al., 2014; Singh et al., 2014; Loumaye et al., 2015; Dong et al., 2016; Kong et al., 2018).