COL1A1 and osteogenesis imperfecta: The Col1a1Jrt/+ OI mouse model is also an autosomal dominant OI mouse model, but differs from the G610C and oim in that it arose from a splice site mutation in the Col1a1 gene, leading to an 18 amino acid deletion near the amino terminal end of proα1(I) collagen (Chen et al., 2014).