CHAT and proximal spinal muscular atrophy: The authors used choline acetyltransferase (ChAT, a marker of αMNs) to stain the SC αMNs in a murine model of SMA and reported that nusinersen could effectively increase the number of ChAT-positive cells by 38%, and up to 62%, with respect to untreated SMA mice, thus proving the recovery of a fraction of the degenerated cell population.