VCP and amyotrophic lateral sclerosis: For instance, the same mutations of the valosin-containing protein (VCP) gene and C9orf 72 appear to be present in individuals with ALS, FTD, and other neurological syndromes (78), and mutations in kinesin family member 5A (KIF5A) are associated with ALS and the Charcot-Marie-Tooth disease (79).