While curing breast cancer during pregnancy would be challenging, the use of PARP inhibitors has garnered much enthusiasm (Okazaki and Moss, 1999; Nathanson and Domchek, 2011), and several such agents have been approved by the FDA for the treatment of patients with ovarian and breast cancers harboring inherited BRCA1 and/or BRCA2 mutations. The gene discussed is BRCA2; the disease is breast cancer.