Similarly, our data in VAT also suggest an impact on vascular function, since MR activation in VAT is known to play a critical role in the development of vascular stiffening and endothelial dysfunction (Nguyen Dinh Cat et al., 2016; Jia et al., 2017; Lefranc et al., 2019). The gene discussed is NR3C2; the disease is endothelial dysfunction.