However, some hints of a potential role of JAK/STAT may come from the evidence of an upregulation of STAT3 in the PB CD4+ and CD8+ T cells of polyarteritis nodosa (PAN) patients and of increased levels of CXCL10 (a STAT induced gene) in active Kawasaki disease (Rimar et al., 2016; Berthelot et al., 2020). The gene discussed is CD8A; the disease is polyarteritis nodosa.