However, we were surprised to find that GLP-1R expression on the surface of macrophages was different in both groups, although the percentage of different phenotypes of macrophages in the CHD group, and the control group was not statistically significant (P < 0.05), compared with the control group, the GLP-1R expression on M2 macrophages was higher in the CHD group, and this seems to indicate that macrophages with anti-inflammatory functions can express more cardiovascular beneficial GLP-1R. The gene discussed is GLP1R; the disease is coronary artery disorder.