CD40 and coronary artery disorder: Last but not least, it is hoped to find disease biomarkers of CHD [30], such as C-reactive protein (CRP), IL-6, serum amyloid A (SAA), CD40/CD40 ligand (CD40L), and heat shock protein 60 (Hsp60) [31] and 70 (Hsp70), but their specificity needs to be improved; therefore, more sensitive and specific inflammatory disease biomarker still need to be studied.