Our data shows that GLP-1R expression levels were indeed higher in total and M2 macrophages in the control group and not the percentage of the inflammatory cells itself, which suggests that GLP-1R may play a more central role than inflammatory cells themselves in the regulation of inflammatory nodes in atherosclerosis; in turn, it also supports the anti-inflammatory effect of GLP-1R in CHD. Here, GLP1R is linked to atherosclerosis.