Gene expression profiling and gene set enrichment analysis (GSEA) of C10 cells versus all other tumor epithelial cells, showed enrichment of (i) stem cell signatures (Fig. 3b), (ii) stemness genes (stem cells, embryonic, mammary stem cells, liver cancer stem cells), cancer radiotherapy responsiveness (Supplementary Figure 2d), as well as target genes of the cancer stem cell gene BMI-1 (Fig. 3b and Supplementary Figure 2d). The gene discussed is BMI1; the disease is cancer.