IGHE and asthma: Treatment with carvacrol improved tracheal responsiveness, inflammatory mediators, total and differential WBC12, serum cytokine and endothelin levels13, and lung pathological changes, immunoglobulin E (IgE) and eosinophil peroxidase levels in the BALF14, serum levels of total protein, phospholipase A2 (Phospholipases A2) and histamine45 in a guinea pig model of asthma as well as genes expression of various cytokines15 and T helper cells subtypes along with their cytokine gene expression16 in and splenocytes of asthmatic mice.