PTEN and glioblastoma: The FGFR3 glioblastoma cases exhibited the most common mutations found in IDH-wild-type glioblastoma [3], with CDKN2A homozygous loss in all cases, followed by PTEN mutations with LOH and CDKN2B homozygous loss, in three cases, and TERT c.124C>T promoter mutation in two cases (Fig. 2a, Additional file 1: Table S2).