PRMT1 and infection: As demonstrated by histologic examination and hematoxylin and eosin (H&E) staining of mice colon tissues, we found that C57BL/6 J-ApcMin/+ mice pretreated with DSS followed by LV infection-mediated PRMT1 knockdown (ApcMin/+-PRMT1KD) developed significantly fewer and smaller visible tumors and microadenomas within their colons than did control scramble-treated mice (ApcMin/+-Ctrl) (Fig. 6b, c, l).