DDIT3 and metabolic dysfunction-associated steatotic liver disease: The CNV region chr12:57897795-57918452 contains the gene encoding CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP), a major transcriptional regulator of endoplasmic reticulum (ER) stress-mediated apoptosis that is implicated in lipotoxicity-induced ER stress and hepatocyte apoptosis in NAFLD [43].