There was no delay in tumor onset in KPPC mice compared to KPPC with heterozygous Zeb1 deletion (KPPC;ZF+) or homozygous Zeb1 deletion (KPPC;ZcKO) as measured by the emergence of a first palpable pancreatic nodule (Figure 6A). The gene discussed is ZEB1; the disease is neoplasm.