ACE and hydrops fetalis: Thanks to the introduction of pharmacological therapies (beta-blockers, angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers, mineralocorticoid receptor antagonists, neprilysin inhibitors, and, recently, sodium-glucose 2 co-transport inhibitors) and devices (implantable cardioverter defibrillator and cardiac resynchronisation therapy), the survival of HF patients has progressively improved.