The results from the univariate analysis found that the high ADAMTS1 and ADAMTS6 mRNA expression were associated with poor survival rates of GC patients (hazard ratio (HR) = 1.52, 95% confidence interval (CI) = 1.09–2.12, P=0.013 and HR = 1.80, 95% CI = 1.29–2.51, P=0.001, respectively) as shown in Table 2. The gene discussed is ADAMTS6; the disease is gastric cancer.