In addition, as shown in Table 3, subgroup analysis indicated that overexpression of the ADAMTS6 genes increased the death rate in GC patients who are ≥60 years old; female patients; patients with gastric antrum cancer; intestinal type adenocarcinoma; G2, G3 histologic grade; microsatellite instability-altitude (MSI-H), MMS; lymph node metastasis; T3, T4 stage; tumor free status; pathologic stage III; R0 resection; those untreated with radiation therapy or targeted therapy, without distant metastasis and HP infection. The gene discussed is ADAMTS6; the disease is metastatic malignant neoplasm in the lymph nodes.