LDHA and Hyperglycemia: Acute hyperglycaemia can in turn significantly alter innate immune responses to infection, and this potentially explains some of the poor outcomes in hospitalized patients who develop hyperglycaemia as a consequence of bacterial and viral infections22 The role of LDH is likely to fit within the same pathway, as increased levels of LDH‐A are seen in immunological Warburg effects when immune cells carry out glycolysis even in the presence of oxygen, resulting in a strong pro‐inflammatory phenotype.23