In the multivariable analysis, tumor stage (stage III vs stage I, HR=2.057, 95% CI 1.355-3.124), especially metastatic stage (stage IV vs stage I, HR=5.518, 95% CI 3.707-8.214), was still a strong prognostic predictor, as expected, and age (p<0.001, HR=1.032, 95% CI 1.017-1.047), expression of GET4 (p=0.002, HR=1.023, 95% CI 1.009-1.038) and CRB3 (p<0.001, HR=0.969, 95% CI 0.960-0.980) were also independent predictive factors. Here, CRB3 is linked to neoplasm.