TSHZ2 and neoplasm: A Kaplan-Meier analysis showed that patients with a high smoking index (p<0.001), no- cVATS operation (p=0.039), high TNM stage (p<0.001), large tumor size (p=0.001), poor differentiation (p<0.001), vascular invasion (p=0.001), negative TSHZ2 expression (p=0.001) or a high Ki67 expression (p=0.001) had a poorer survival outcome than others, according to a log-rank test (Table 2).