Table 5 shows that compared to the IFN-λ4-Null group, the risks of gastrointestinal infection and malaria but not respiratory infection were increased in the following order: weak IFN-λ4-S70 < one copy of strong IFN-λ4-P70 < two copies of strong IFN-λ4-P70 protein. Here, IFNL4 is linked to respiratory tract infectious disorder.