APOE and Mental deterioration: By contrast, APOE-\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\varepsilon $$\end{document}ε4 carriers also exhibit earlier and more pronounced alterations of their hippocampus (45 months ealier and 1.17 times faster in carriers compared to non-carriers), but this effect is, to some extend, alleviated in the onset of cognitive decline which does not occur earlier in carriers than in non-carriers.