For each modality, we perform a multivariate linear regression between each individual parameters and genetic, biological and environmental factors: sex, APOE-\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\varepsilon $$\end{document}ε4 genotype, presence of amyloidosis, marital status and education level. This evidence concerns the gene APOE and amyloidosis.