TARDBP and dementia: For example, co-occurrence of Lewy body pathology has been observed in more than half of patients with a clinical diagnosis of bvFTD who were neuropathologically diagnosed with AD.32 However, in our study only one case had a coprimary neuropathological diagnosis of dementia with Lewy bodies in addition to AD, and this low frequency is in accordance with previous pathological findings in clinically defined bvAD.1 Importantly, TDP-43 or isolated 3R tau inclusions were not found in our bvAD cases.