IL1RN and Sepsis: Figure 8 summarizes the pairwise fold changes for individual genes. Two-thirds of the DEGs in the infection experiment were also represented among the DEGs in the LPS experiment. We noted again the substantial upregulation of Slpi and Ibsp. Other coding sequences upregulated under both conditions were Acod1, Alox5, Arg1, Cxcl2, Il1rn, Il1b, Lcn2, and Mmp8. A discordant DEG was dual-specificity phosphatase (Dusp), which has been implicated in regulating lipid metabolism during sepsis (43).