Consistent with the results of the above experiments, the expression of osteogenic genes (Fig. 4a) including bone morphogenetic protein 2 (BMP2), bone sialoprotein (BSP), runt-related gene 2 (Runx2), osteocalcin (OCN) and osteopontin (OPN), also confirmed that BMSCs treated with EMF showed more significant osteogenic capacity under OM. Here, IBSP is linked to ocular melanoma.