RT-PCR analysis of PD-L1-lnc expression in the implanted tumor tissues confirmed that PD-L1-lnc A549 tumors and PD-L1-lnc shRNA A549 tumors expressed significantly higher and lower levels of PD-L1-lnc, respectively, compared to control A549 lung cancer tissues (Fig. 5e). The gene discussed is CD274; the disease is lung cancer.