PGR and neoplasm: In a subgroup analysis, a high amount of BATMs was a negatively associated with OS independent of tumor foci (in unifocal tumors: Additional file 1a, n = 117, p = 0.006 and in multifocal and multicentric tumors: additional file 1b, n = 103, p = 0.025) and independent of PR status (in PR positive tumors: Additional file 1d, n = 131, p = 0.041 and in PR-negative tumors, Additional file 1e, n = 89, p = 0.005).