At each step of the psoriasis molecular pathway, different inflammatory cytokines such as IL-6, IL-17, IL-22, and IL-23 are triggered, on the other side, growth factors such as EGF, VEGF, KGF, and IGF-1, which underscores the central role which predominantly drives epidermal hyperplasia [12, 56, 57]. This evidence concerns the gene IGF1 and psoriasis.