Among mothers with hypercholesterolemia, maternal and newborn plasma HDL and HDL2 cholesterol, apolipoprotein (Apo)A1, degree of fatty acid unsaturation, linoleic acid (%), docosahexaenoic acid (%), alanine, glutamine, isoleucine, leucine, valine, creatinine, and particle concentration of medium HDL were significantly positively associated (multivariable 0.001 ≤ q ≤ 0.09, Fig. 3 and Additional file 4). This evidence concerns the gene APOA1 and familial hypercholesterolemia.