In addition, the following variants were significantly associated with acne risk: ADH7 (alcohol dehydrogenase 7) rs1154469 [38], SRD5A2 (steroid 5 alpha-reductase 2) TA repeat VNTR [57] and VDR (vitamin D receptor) rs731236 and rs7975232 [58]. This evidence concerns the gene ADH7 and acne.