PINX1 and acne: It is also unclear how PINX1, which has functions in telomere length maintenance and chromosome stability [95]; F13A1, which encodes coagulation factor XIII, the last zymogen to become activated in the blood coagulation cascade and a transglutaminase enzyme [96]; BCL11A, a transcription factor involved in hematopoietic development [97]; FGF2, which is involved in processes that contribute to scar formation and wound healing [11]; and SUGCT, which encodes an enzyme that converts glutarate to glutaryl-CoA [98] may influence the pathogenesis of acne.