CDKN2B and breast cancer: Although different CDKN2B-AS1 genotypes in the control group showed no significant difference in gene relative expression (P = 0.069) (Fig. 2d), the G/G genotype was associated with a higher expression level than A/G in the BC cohort; median and quartile values were 3.14 (1.52–4.25) in G/G vs. 1.42 (0.93–2.35) in A/G and 1.62 (1.33–2.51) in A/A (P = 0.006) (Fig. 2e).