Second, we chose a cardiomyocyte-specific cTnT promoter to control the expression of miR-30 in AAV2/9-miR-30-Zsgreen (Supplemental Figure 3); therefore, AAV2/9-miR-30-Zsgreen-injected CKD rats showed reduced cardiac hypertrophy, suggesting that cardiomyocyte-expressed miR-30 is directly responsible for this effect. The gene discussed is TNNT2; the disease is chronic kidney disease.