Wang et al. (10) concluded that some other detrimental factors, such as FGF-23, uremic toxin, Ang II and TGF-β, are involved in CKD-induced cardiac hypertrophy, and our results showed that treating cardiomyocytes with such stimuli can reduce miR-30 expression (Figure 7, E–G). Here, FGF23 is linked to cardiac hypertrophy.