Two established markers of cardiac hypertrophy, atrial natriuretic peptide (Anp) and brain natriuretic peptide (Bnp) (38), in the AAV2/9-miR-30-Zsgreen–treated rats were decreased compared with those of AAV2/9-Zsgreen–injected rats (Figure 3, G and H). This evidence concerns the gene NPPB and cardiac hypertrophy.