Diabetes mellitus (DM) and cardiovascular disease (CVD) often co-exist.[1] Percutaneous coronary intervention (PCI) has commonly been used to treat patients with CVD.[2] Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor such as clopidogrel or ticagrelor has been used to prevent cardiovascular complications following PCI.[3]. Here, P2RY12 is linked to diabetes mellitus.