Finally, because USP24 promotes lung cancer malignancy, we also studied the effects of NCI677397, NCI158067, and other compounds from the NCI library in blocking lung cancer migration (Supplementary Figs. 18 and 19), and the data indicated that both NCI677397 and NCI158067 could inhibit lung cancer migration, but the other compounds not. This evidence concerns the gene USP24 and lung carcinoma.