Studies by Xiang Fei et al.31 and Xiaoli Fan et al.19 on Chinese autoimmune diseases and AIH patients also showed that NUDT15 c.415C>T SNP is significantly related to AZA-induced early leukopenia (P = 1.79 × 10−7; OR = 7.59 and P < 0.00001; OR = 20.41, respectively). This evidence concerns the gene NUDT15 and autoimmune disease.