TP53 and neoplasm: Positive pN status (p = 0.0040) and higher UICC stage (stage ≥ II, p = 0.0036), presence of TP53 mutation (HR: 2.13, p = 0.0033), and tumor relapse (HR: 2.75, p < 0.0001) were prognostic indicators (Table 1).