As a first approach to a better understanding of TXNIP functions in melanoma, we quantified its expression in metastatic melanoma of commercially available melanoma cDNA arrays, as well as in two publicly available NCBI GEO microarray datasets (GSE46517 and GSE3189, chosen for high sample numbers and unequivocal experimental design) of benign melanocytic nevi (BMN), primary (PM) or metastatic (MM) melanomas. Here, TXNIP is linked to metastatic melanoma.