Next, we used the following criteria and analyses and identified NEDD4L (neural precursor cell-expressed developmentally downregulated 4 like) as a potential m6A target of arsenic, m6A modification, and FTO: (1) decreased m6A enrichment, (2) altered mRNA level, (3) potential role in cancer, and (4) altered expression in both human and mouse SCC. This evidence concerns the gene FTO and cancer.