Interestingly, although langerin+ cDC2 did not express higher levels of CCR5 (Fig. 9A) or CD4 (Fig. 9B) than their langerin− counterparts, they nevertheless produced higher levels of both HIV lab-adapted BaL strain and a transmitted funder strain after 96 h indicating they supported higher levels of infection (Fig. 9C) and we were able to block this effect with AZT (Fig. 9D). The gene discussed is CCR5; the disease is infection.