APOE and Alzheimer disease: Given that glial specific signals arose from APOE3 and APOE4 strata, we therefore primarily focused on RRA cortex candidates showing evidence of association with AD in any glial cell type (astrocytes, microglia, oligodendrocytes and oligodendrocyte precursors) within the same APOE stratum (Figure 6 and Supplementary Table 39 and Supplementary Figures 13–16).