In addition, initial increased IL-6 concentration was correlated with initial severity as measured by sepsis-related organ failure assessment (SOFA) score and with intensity of pulmonary dysfunction as measured by the ratio between partial pressure of oxygen in arterial blood (PaO2) and fraction of inspired oxygen (FiO2) (PaO2/FiO2 ratio, Fig. 1b). Here, IL6 is linked to Sepsis.