CRKL and psychiatric disorder: The contribution of the 1.4-Mb deletion for the onset of psychiatric disorders has been suggested in clinical studies [7, 9–11], and Crkl (CRK-like Proto-Oncogene, Adaptor Protein) heterozygous-deficient mice (Crkl+/−) have been analyzed to investigate the contributions of Crkl gene to behavioral phenotypes relevant to psychiatric disorders [43].